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Before preparing and injecting BYDUREON, first read the Instructions for Use. This is a step-by-step guide that comes with your prescription and includes easy-to-follow pictures of the process. Follow the instructions completely and carefully each time you use BYDUREON.

Explore the tabs below to learn more about where and when to use BYDUREON. You can also learn about proper storage and disposal. If at any time you have questions about your BYDUREON treatment, talk to your healthcare provider.

Where to Inject BYDUREON

Inject BYDUREON under the skin (subcutaneously), not into a muscle or vein. You can administer the injection in your stomach area (abdomen), your thigh, or the back of your upper arms. Each week you can use the same general area of your body. Just be sure not to inject in the exact same place.

You may notice itching or redness at the injection site. Serious injection-site reactions, with or without bumps (nodules), have happened in some people who use BYDUREON. Some of these injection-site reactions have required surgery. Call your healthcare provider if you have any symptoms of injection-site reactions, including severe pain, swelling, blisters, an open wound, or a dark scab.

Areas on body for injection
Information about small, raised bumps

When to Inject BYDUREON

BYDUREON should be used once every 7 days.

Choosing Your Dosing Day

You can choose to inject your first dose on any day of the week. Then you’ll inject it on the same day each week. This is your "dosing day." You can inject BYDUREON at any time during your dosing day, with or without food.

Try to select a day and time that best fits into your weekly schedule and is easy to remember. It can help to choose a dosing day that is linked to a regular weekly activity. For example, if you have a favorite TV show you watch on Friday nights, you could plan to inject your BYDUREON dose on Friday.

Changing Your Dosing Day

If you want to change your dosing day, you can. When changing the dosing day, you can choose any day you want; however, the next dose must be injected at least 3 days after the previous dose. Do not inject 2 doses of BYDUREON less than 3 days apart.

Changing your dosing day

Example: How to change your dosing day from Friday to Sunday.

For example, let’s say you want to change your dosing day from Friday to Sunday. Give yourself a dose of BYDUREON on Friday, as scheduled. Because Sunday is less than 3 days from your original dosing day, you should inject your next dose of BYDUREON on the following Sunday (see calendar above).

Once you’ve selected a dosing day that works for you, try to stay with it. It’s not a good idea to change your dosing day often.

Missing an Injection

If you miss an injection of BYDUREON on your dosing day, give yourself an injection as soon as you can, unless your next dosing day is 1 or 2 days away. In that case, wait until your next regular dosing day. Then inject your next dose on your regular dosing day. Don’t inject 2 doses less than 3 days apart.

How to Store BYDUREON

It is important that you carefully follow all storage instructions for BYDUREON.


  • BYDUREON should be stored in your refrigerator at 36°F to 46°F (2°C to 8°C) and protected from light until prepared for use
  • Do not freeze BYDUREON. Do not use BYDUREON if it has been frozen
  • Do not use BYDUREON past the expiration date
  • Keep BYDUREON, and all medicine, out of reach of children
  • If needed, you can keep the BYDUREON out of the refrigerator at 68°F to 77°F (20°C to 25°C) for up to 4 weeks
Sharps container

Disposal Instructions

Proper disposal of needles is important for your safety and the safety of those around you.

  • Use a biohazard container made specifically for disposing of used injection devices (called a “sharps” container) or a puncture-resistant container to throw out the device with the needle still attached. To avoid a needlestick injury, do not put the cover back on the needle
  • Throw away all other parts in the trash. You do not have to save them
  • Check with your healthcare provider or pharmacist for instructions about the right way to dispose of used injection devices. There may be special local or state laws about how to dispose of used injection devices and/or puncture-resistant containers

Start Saving Today!*

Activate or request your BYDUREON SavingsRx Card here.

*Eligibility Requirements and terms of use apply.


Watch and Learn

View a video on how to use BYDUREON.

SteadySTART Program

Meet with a Clinical Educator in person and learn how to get started with BYDUREON.