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How to use BYDUREON

Your healthcare provider should show you how to use BYDUREON before you use it for the first time. Then, when you are ready to administer BYDUREON yourself, the information in this section will help you.

Before preparing and injecting BYDUREON, first read the Instructions for Use. This is a step-by-step guide that comes with your prescription and includes easy-to-follow pictures of the process. Follow the instructions completely and carefully each time you use BYDUREON. You may also download the Instructions for Use here.

Instructions for Use (PDF)

You will find instructions for the BYDUREON Single-dose Pen on page 52 and instructions for the Single-dose Tray on page 34.

We also recommend that you view the videos below before using the BYDUREON Single-dose Pen or BYDUREON Single-dose Tray.

BYDUREON Step-by-Step Demonstration Videos

Watch a step-by-step video on how to use the BYDUREON Single-dose Pen

Watch a step-by-step video on how to use the BYDUREON Single-dose Pen

BYDUREON Single-Dose Pen Video

BYDUREON Single-dose Tray

Explore this information to learn more about where and when to use BYDUREON. You can also learn about proper storage and disposal. If at any time you have questions about your BYDUREON treatment, talk to your healthcare provider. For assistance, you may also call a BYDUREON Care Partner toll-free at 1-844-929-3736.

Learn More About Where and When to Use BYDUREON

Where to inject BYDUREON

Please note that BYDUREON must be injected right after you mix it.

  • Inject BYDUREON under the skin (subcutaneously), not into a muscle or vein, exactly the way your healthcare provider instructed you to. You can do the injection in your stomach area (abdomen), your thigh, or the back of your upper arms

  • After injecting with the BYDUREON Single-dose Pen, make sure you hold the needle in your skin for 10 seconds to get the full dose

  • Each week you can use the same general area of your body. Just be sure not to inject in the exact same place

About injection site bumps

After injecting BYDUREON, you may see or feel a small, raised bump at the injection site within 2-4 weeks (see visual below). This is your body reacting to the microspheres that hold the medicine as it works to dissolve them. These bumps rarely need medical attention, and do not interfere with BYDUREON treatment. They generally go away within 3 to 6 weeks.

But keep in mind that these more common bumps are different from serious injection-site reactions that may include severe pain, swelling, blisters, an open wound, or a dark scab at the injection site. Some of these injection-site reactions have required surgical intervention. Call your healthcare provider right away if you experience any of these reactions.

Where to inject BYDUREON

When to inject BYDUREON

How to store BYDUREON


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