
To help lower blood sugar, along with diet and exercise, in adults with type 2 diabetes who are not at goal with oral diabetes medications
Most people—in fact 85% who were part of a study—agreed that once-weekly BYDUREON BCise is easy or very easy to use.
It’s a non-insulin medicine in an injectable device holding just one dose. You won’t have to increase your dose and there’s no need to adjust a dial (no dose dialing). Plus, the hidden needle is already attached for you.
Dosing day *After 10 weeks of continued once-weekly dosing, BYDUREON BCise keeps a consistent level of medicine in your body, working for you 7 days a week.
Simply mix, unlock, unscrew the cap, and push against skin to inject*—the device does the rest to complete the dose.
Do not unlock the device yet. With the orange cap pointing up, shake the device up and down hard for at least 15 seconds. It must be evenly mixed to get the full dose.
Continue to hold the device upright. Turn the knob from the “Lock” position to the “Unlock” position. You will hear a “click”.
As you hold the device straight up, unscrew the orange cap in a counterclockwise direction. Do not pull.
Push the device firmly against your skin. You will hear a click when the injection begins. Keep the device pressed against your skin for 15 seconds to make sure you get the full dose. You can inject into your stomach, thigh, or back of the upper arm.
*Following preparation.
Please see the full Instructions for Use for complete instructions as well as the Medication Guide.
Disposal of your device: Put your used autoinjector in an FDA-cleared sharps disposal container right away after use. Do not throw away (dispose of) loose needles and syringes into your household trash.
Watch this instructional video.
Before you use the device for the first time, please read the full
Instructions for Use to feel extra confident.
Some adults taking BYDUREON BCise can get a small raised bump under their skin at the injection site. This is a normal body response to the tiny beads in BYDUREON BCise that slowly release medicine over time, and the bump usually disappeared in an average of 4 weeks in BYDUREON clinical studies.
Serious injection-site reactions, with or without bumps (nodules), have happened in some people who use BYDUREON. Some of these injection-site reactions have required surgery. Call your healthcare provider if you have any symptoms of an injection-site reaction, including severe pain, swelling, blisters, an open wound, or a dark scab.
Have questions about how to use BYDUREON BCise®? Or injecting for the first time? Feel free to talk or video chat with one of our BYDUREON BCise nurses for the support you need.
*AstraZeneca cannot provide medical advice and can only provide information about AstraZeneca medications. Decisions regarding your health and treatment of your condition should be made with your own healthcare provider.
Some of the most commonly asked questions about BYDUREON BCise®.
For detailed instructions, see the full Instructions for Use that comes with your BYDUREON BCise prescription.
You can watch a short instructional video demonstrating how to use the BYDUREON BCise device here.
If you have questions about how to use BYDUREON BCise, you can speak to a nurse by calling 1-844-MY-BCISE (1-8-4-4-692-2473) (8 AM to 8 PM ET, Monday through Friday and 10 AM to 6 PM, Saturday and Sunday). You can also speak directly to a nurse through video chat who can demonstrate the injection technique and even watch as you perform your own injection.
Click here for more details.*
*AstraZeneca cannot provide medical advice and can only provide information about AstraZeneca medication. Decisions regarding your health and treatment of your condition should be made with your own healthcare provider.
If you miss an injection of BYDUREON BCise on your dosing day, give yourself an injection as soon as you can, unless your next dosing day is 1 or 2 days away. In that case, wait until your next regular dosing day. Then inject your next dose on your regular dosing day. Don’t inject 2 doses less than 3 days apart.
The needle is attached to the device and covered by the orange cap. When you unscrew the orange cap when taking BYDUREON BCise, a green shield pops up from the device to keep the needle covered until you inject.
For detailed storage instructions, see the Instructions for Use that comes with your BYDUREON BCise prescription.
Some adults taking BYDUREON BCise can get a small raised bump under their skin at the injection site. This is a normal body response to the tiny beads in BYDUREON BCise that slowly release medicine over time. The bump usually disappeared in an average of 4 weeks in clinical studies with BYDUREON, another formulation of exenatide extended-release.
Serious injection-site reactions, with or without bumps (nodules), have happened in some people who use BYDUREON. Some of these injection-site reactions have required surgery. Call your healthcare provider if you have any symptoms of an injection-site reaction, including severe pain, swelling, blisters, an open wound, or a dark scab.
When you sign up for your BYDUREON BCise Savings Card, saving on your prescription is just the beginning. You’ll also be automatically enrolled in our support program to help you manage the ins and outs of type 2 diabetes.
*Pay as low as $0 for as long as your doctor prescribes BYDUREON BCise. See eligibility requirements. Restrictions apply.
Sign upBYDUREON (exenatide extended-release) and BYDUREON BCise may cause serious side effects, including:
The most common side effects with BYDUREON may include nausea, diarrhea, headache, vomiting, constipation, itching at the injection site, a small bump (nodule) at the injection site, and indigestion.
The most common side effects with BYDUREON BCise may include a bump at the injection site and/or nausea. Nausea is most common when you first start using BYDUREON or BYDUREON BCise, but decreases over time in most people as their body gets used to the medicine.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements, as taking them with BYDUREON or BYDUREON BCise may affect how each medicine works.
Before using BYDUREON or BYDUREON BCise, tell your healthcare provider if you are pregnant, nursing, or plan to become pregnant or nurse. BYDUREON or BYDUREON BCise may harm your unborn baby.