To help lower blood sugar, along with diet and exercise, in adults with type 2 diabetes who are not at goal with oral diabetes medications
After 10 weeks of continued once-weekly dosing, BYDUREON BCise is ready to work when you need it, keeping a consistent level of medicine in your body, working for you 7 days a week.
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As you keep up with your hectic life, it’s important to keep in mind that type 2 diabetes can progress over time. So, you may need a different approach to your treatment to help manage blood sugar highs and lows—and reach your A1C goal.
BYDUREON BCise® is a non-insulin, once-a-week injectable that works all week long.* Along with diet and exercise, it has been proven to significantly lower A1C.
Here are some of the key benefits of BYDUREON BCise:
Non-insulin injectable
Reduced up to 1.4%
Weight reduced up to 3 lbNot a weight-loss drug.
Cardiovascular-safe†In 2 clinical studies lasting 28 weeks, BYDUREON BCise lowered A1C by an average of 1.1% and 1.4% from an average starting A1C of 8.4% and 8.5%, respectively, when used alone or with certain oral type 2 diabetes medicine(s). Your results may vary
In the same studies, BYDUREON BCise lowered weight by an average of 3 lb from average starting weights of 196 and 213 lb. BYDUREON BCise is not a weight-loss drug
In another clinical study, including patients with and without established cardiovascular disease, it was proven that BYDUREON does not increase the risk of major cardiovascular events like heart attack, stroke or cardiovascular death. BYDUREON BCise is not approved to reduce the risk of CV events or death
*After 10 weeks of continued once-weekly dosing, BYDUREON BCise keeps a consistent level of medicine in your body, working for you 7 days a week.
†EXenatide Study of Cardiovascular Event Lowering Trial (EXSCEL) evaluated cardiovascular outcomes after patients were treated with BYDUREON®, another formulation of exenatide extended-release.
The most common side effects with BYDUREON BCise® include a bump at the injection site and nausea. Other side effects that occur less often include headache, diarrhea, vomiting, injection-site itching and redness, dizziness, and constipation. Serious injection-site reactions have happened in some people who use BYDUREON. These are not all the possible side effects of BYDUREON BCise. See the Important Safety Information below for more information and talk to your healthcare provider if you have any side effects that bother you or do not go away.
BYDUREON BCise is slowly released into your body—over time—through an extended-release delivery system. See for yourself how it’s ready to work when you need it to help lower your blood sugar.*
*Following 10 weeks of once-weekly dosing when the level of medicine in your body
should be at the optimal level.
BYDUREON BCise releases the medicine gradually and continually over time. With each weekly dose, the amount of medicine in your body builds up until it reaches an optimal level after 10 weeks, to help give you consistent control of your blood sugar 7 days a week.
BYDUREON BCise is a type 2 diabetes medicine that is slowly released into your body over time, working to help your body release its own insulin when it’s needed to help lower blood sugar.
With type 2 diabetes, a hormone called glucagon causes the liver to make sugar when it's not needed. BYDUREON BCise mimics the actions of GLP-1, a natural hormone, to help prevent the release of glucagon.
With type 2 diabetes, the stomach moves food along faster than it should, and that sends sugar into the blood faster. BYDUREON BCise works to slow down how quickly the stomach empties sending sugar into the blood stream more slowly.
With type 2 diabetes, too little insulin is produced by the pancreas to keep blood sugar levels normal. BYDUREON BCise mimics the GLP-1 hormone to help your pancreas release insulin when blood sugar needs to go down.*
See The Inside Story video and learn how BYDUREON BCise works with your body.
*After 10 weeks of continued once-weekly dosing, BYDUREON BCise keeps a consistent level of medicine in your body, working for you 7 days a week.
While type 2 diabetes may not be easy to manage, talking to your doctor should be.
Want help for your discussion?
If you’re frustrated with your blood sugar highs and lows, ask your doctor if BYDUREON BCise, along with diet and exercise, could help give you consistent control of your blood sugar.
Doing your best to manage type 2 diabetes is not easy, but it’s important. Along with diet and exercise, BYDUREON BCise has been proven to significantly lower A1C. And although it’s not a weight-loss drug, BYDUREON BCise may help you lose some weight.
In 2 clinical studies lasting 28 weeks, BYDUREON BCise lowered A1C by an average of 1.1% to 1.4% from an average starting A1C of 8.4% to 8.5%, respectively, when used alone or with certain oral type 2 diabetes medicines(s). Your results may vary
In the same studies, BYDUREON BCise lowered weight by an average of 3 lb from average starting weights of 196 and 213 lb. Your results may vary. BYDUREON BCise is not a weight-loss drug
The most common side effects were a bump at the injection site and nausea.
Over time, type 2 diabetes may progress, leaving you feeling frustrated about getting to your A1C goal. It’s normal to feel uneasy about starting a conversation with your doctor. So, use these talking points as your guide, and make a list of concerns about your current treatment plan before your visit.
Even if you feel you are staying on track, let your doctor know. These are the types of discussions doctors want to hear about, too.
Some of the most commonly asked questions about BYDUREON BCise®.
BYDUREON BCise may cause serious side effects, including:
POSSIBLE THYROID TUMORS, INCLUDING CANCER: Tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In animal studies, BYDUREON and medicines that work like it caused thyroid tumors, including thyroid cancer. It is not known if BYDUREON BCise will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people.
Do not use BYDUREON BCise if you or any of your family members have ever had MTC or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
See additional Important Safety Information.
BYDUREON BCise has been proven to help significantly lower A1C along with diet and exercise. Also, although not a weight-loss drug, BYDUREON BCise may help you lose some weight.
In one clinical study lasting 28 weeks, BYDUREON BCise lowered A1C by an average of 1.4% from an average starting A1C of 8.5% and lowered weight by an average of 3 lb from an average starting weight of 213 lb when used alone or with certain oral type 2 diabetes medicine(s). In a second clinical study, BYDUREON BCise lowered A1C by an average of 1.1% from an average starting A1C of 8.4% and lowered weight by an average of 3 lb after 28 weeks from an average starting weight of 196 lb when added to metformin. Your results may vary.
BYDUREON BCise has convenient once-weekly dosing and an extended-release delivery system. Each dose contains tiny beads that slowly dissolve to continuously release medicine into your body over time, helping your body release its own insulin, when needed, to help lower blood sugar.
After 10 weeks of continued once-weekly dosing, BYDUREON BCise keeps a consistent level of medicine in your body, working for you 7 days a week.
BYDUREON BCise works gradually and continually. As you continue to take your weekly doses, the amount of medicine in your body gradually builds up over 10 weeks until it reaches an optimal level to work in your body. With continued once-weekly dosing, the extended-release delivery system of BYDUREON BCise keeps a consistent level of medicine in your body, ready to work when you need it to help lower your blood sugar.
Remember, you need to continue to take BYDUREON BCise exactly as your doctor or healthcare provider has prescribed it, along with continuing to follow the treatment plan they’ve recommended.
Pay as low as $0 every month with your prescription for BYDUREON BCise®.* Offer subject to Savings Eligibility Requirements and Program Terms of Use.
When you download your savings card, you can sign up for customized patient support, including helpful tips and dosing reminders sent right to your email or through a text message.
BYDUREON® (exenatide extended-release) and BYDUREON BCise may cause serious side effects, including:
The most common side effects with BYDUREON may include nausea, diarrhea, headache, vomiting, constipation, itching at the injection site, a small bump (nodule) at the injection site, and indigestion.
The most common side effects with BYDUREON BCise may include a bump at the injection site and/or nausea. Nausea is most common when you first start using BYDUREON or BYDUREON BCise, but decreases over time in most people as their body gets used to the medicine.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements, as taking them with BYDUREON or BYDUREON BCise may affect how each medicine works.
Before using BYDUREON or BYDUREON BCise, tell your healthcare provider if you are pregnant, nursing, or plan to become pregnant or nurse. BYDUREON or BYDUREON BCise may harm your unborn baby.
