To help lower blood sugar, along with diet and exercise, in adults with type 2 diabetes who are not at goal with oral diabetes medications

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You keep going 7 days a week. Shouldn’t your medicine keep working all week, too?
One dose. Once a week. Lasts all week.*
pen art Once-weekly BYDUREON BCise injector for adults with type 2 diabetes.

With your busy life, wouldn’t it be convenient to take one dose, once a week, and have it last all week?* That’s what you can get with BYDUREON® BCise®. Along with diet and exercise, BYDUREON BCise may help lower A1C for adults with type 2 diabetes. And although it’s not a weight-loss drug, it may help you lose some weight.†

*After 10 weeks of continued once-weekly dosing, BYDUREON BCise keeps a consistent level of medicine in your body, working for you 7 days a week.

†Lowered weight by an average of 3 lbs in 2 clinical studies lasting 28 weeks when used alone or with certain oral type 2 diabetes medications. Your results may vary.

Learn more about BYDUREON BCise
BYDUREON BCise uses microsphere technology to help deliver a consistent level of medicine.
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BYDUREON BCise contains tiny beads that store the medicine inside. As the beads dissolve, they release the medicine continuously into your body over time.* This is how BYDUREON BCise offers a consistent level of medicine to help lower your blood sugar.

*Following 10 weeks of once-weekly dosing when the level of medicine in your body should be at the optimal level.

It’s ready to work—when you need it

BYDUREON BCise helps your body release its own insulin when it’s needed to help lower your blood sugar. This means the medicine is ready to work when your body needs it.

See how BYDUREON BCise works
BYDUREON BCise is not a weight loss medicine
BYDUREON BCise is not a weight loss medicine
BYDUREON BCise may help lower blood sugar

In 2 clinical studies lasting 28 weeks, BYDUREON BCise lowered A1C by an average of 1.1% and 1.4% from a starting A1C of 8.4% and 8.5% when used alone or with certain oral type 2 diabetes medicines. In addition, although not a weight-loss drug, it lowered weight by an average of 3 lbs from a starting weight of 196 and 213 lbs in those clinical studies. Your results may vary.

Common Adverse Reactions

The most common adverse reactions with BYDUREON BCise include a bump at the injection site and nausea. Other side effects that occur less often include headache, diarrhea, vomiting, injection site itching and redness, dizziness, and constipation. Serious injection site reactions have happened in some people who use BYDUREON BCise. These are not all the possible side effects of BYDUREON BCise. See the Important Safety Information below for more information and talk to your healthcare provider if you have any side effects that bother you or do not go away.

Save on your prescription
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You can pay as low as $0 every month‡ with your prescription for BYDUREON BCise. Just register for the BYDUREON Savings Program and you'll also have access to our support team for help along the way.

Learn more about savings

‡See eligibility requirements. Restrictions apply.

How to use BYDUREON BCise

There are 3 simple steps* to using the BYDUREON BCise device:

Watch the video

*Following preparation.

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IMPORTANT SAFETY INFORMATION

IMPORTANT SAFETY INFORMATION

BYDUREON BCise may cause serious side effects, including:

  • POSSIBLE THYROID TUMORS, INCLUDING CANCER Tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In animal studies, BYDUREON and medicines that work like it caused thyroid tumors, including thyroid cancer. It is not known if BYDUREON BCise will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people

  • Do not use BYDUREON BCise if you or any of your family members have ever had MTC or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

  • Do not use BYDUREON BCise if you have had an allergic reaction to exenatide or any of the other ingredients in BYDUREON BCise

  • Inflammation of the pancreas (pancreatitis) Stop using BYDUREON BCise and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting. You may feel the pain from your abdomen to your back

  • Low blood sugar (hypoglycemia) Your risk for getting low blood sugar may be higher if you use BYDUREON BCise with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. Tell your healthcare provider if you take other diabetes medicines. Talk to your healthcare provider about managing low blood sugar. Signs and symptoms of low blood sugar include dizziness or lightheadedness, sweating, confusion or drowsiness, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability, mood changes, hunger, weakness, or feeling jittery

  • Kidney problems (kidney failure) Tell your healthcare provider if you have or had kidney problems. In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration) which may cause kidney problems to get worse

  • Stomach problems Tell your healthcare provider if you have severe stomach problems, such as slowed emptying of your stomach (gastroparesis) or problems digesting food. Other medicines like BYDUREON BCise may cause severe stomach problems. It is not known if BYDUREON BCise causes or worsens stomach problems

  • Serious allergic reactions Stop using BYDUREON BCise and get medical help right away if you have any symptoms of a serious allergic reaction, including itching, rash, or difficulty breathing

  • Injection-site reactions Serious injection-site reactions, with or without bumps (nodules), have happened in some people who use BYDUREON BCise. Some of these injection-site reactions have required surgery. Call your healthcare provider if you have any symptoms of injection-site reactions, including severe pain, swelling, blisters, an open wound, or a dark scab

The most common side effects with BYDUREON BCise may include a bump at the injection site and/or nausea. Nausea is most common when you first start using BYDUREON BCise, but decreases over time in most people as their body gets used to the medicine.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements, as taking them with BYDUREON BCise may affect how each medicine works.

Before using BYDUREON BCise, tell your healthcare provider if you are pregnant, nursing, or plan to become pregnant or nurse. BYDUREON BCise may harm your unborn baby.

APPROVED USES

  • BYDUREON BCise is an injectable prescription medicine that may improve blood sugar (glucose) in adults with type 2 diabetes mellitus, and should be used along with diet and exercise

  • BYDUREON BCise is not recommended as the first choice of medicine for treating diabetes

  • BYDUREON BCise is not a substitute for insulin and is not for people with type 1 diabetes or people with diabetic ketoacidosis

  • Do not use BYDUREON, BYDUREON BCise, BYETTA or other medicines containing exenatide together

  • It is not known if BYDUREON BCise can be used in people with a history of pancreatitis

Please click here for Medication Guide, and click here for Full Prescribing Information.

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